A Review Of phenobarbital sodium powder
A Review Of phenobarbital sodium powder
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pentobarbital will minimize the extent or effect of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Keep track of Intently (1)pentobarbital will minimize the level or effect of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Loss of, or reduced reaction to tofacitinib may possibly take place when coadministered with strong CYP3A4 inducers
pentobarbital will lower the extent or effect of duvelisib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration with a powerful CYP3A inducer decreases duvelisib space under the curve (AUC), which can minimize duvelisib efficacy.
pentobarbital will reduce the extent or effect of linagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Utilization of alternative solutions is strongly advisable when linagliptin would be to be administered with a CYP3A4 inducer
pentobarbital will decrease the extent or effect of atorvastatin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lower the extent or effect of armodafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.
Monoamine oxidase inhibitors (MAOI): MAOI prolong the effects of barbiturates probably for the reason pentobarbital sodium mice that metabolism on the barbiturate is inhibited.
pentobarbital will decrease the extent or effect of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Strong CYP3A4 inducers might lessen suvorexant efficacy; if enhanced suvorexant dose essential, will not exceed 20 mg/working day
Contraindicated (one)pentobarbital decreases levels of vandetanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration with strong CYP3A4 inducers; these drugs lower exposure to vandetanib by nearly 40%.
Use in pregnancy: Barbiturates can result in fetal hurt when administered to some Expecting lady. Retrospective, case-controlled studies have suggested a link in between the maternal use of barbiturates and a better than expected incidence of fetal abnormalities. Pursuing oral or parenteral administration, barbiturates easily cross the placental barrier and so are distributed in the course of fetal tissues with greatest concentrations present in the placenta, fetal liver, and Mind.
pentobarbital will lower the extent or effect of etonogestrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lessen the extent or effect of rabeprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.
pentobarbital will lessen the extent or effect of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Sturdy or average CYP3A4 inducers may possibly increase fee of diazepam elimination; thus, efficacy of diazepam could be lessened.
The sodium salt occurs being a white, somewhat bitter powder which is freely soluble in water and alcohol but almost insoluble in benzene and ether.